Energy · Recovery · Healthy Aging

NAD+ Therapy Explained

The coenzyme behind cellular energy, DNA repair and healthy aging — and how to start your first NAD+ plan.

Why People Start NAD+
  • Powers mitochondrial energy production and DNA repair
  • NAD+ levels decline significantly with age
  • Delivered as a clinician-prescribed injectable, compounded at a licensed pharmacy

What is NAD+?

NAD+ — Nicotinamide Adenine Dinucleotide — is a coenzyme central to cellular energy production, DNA repair, and metabolic function. It's found in every cell in your body and acts as a key player in the reactions that convert the food you eat into the energy your cells run on.

NAD+ powers mitochondrial energy production and DNA repair. Levels decline significantly with age, impairing cellular function across every tissue. Restoring NAD+ may support sustained energy, mental clarity, and healthy cellular aging.

The short version

Think of NAD+ as the fuel your cells use to make energy and keep themselves in good repair. Because levels drop as we age, some people choose to supplement it — clinically used to support energy, focus, and healthy aging.

Pricing

NAD+ plans are transparent and flat — no insurance required. Base pricing matches our treatments page; use code NAD20 at checkout for 20% off below.

Monthly $199 $159 / month

Quarterly $549 $439 / 3 months

6 Months $899 $719 / 6 months

20% off with code NAD20 at checkout

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Benefits of NAD+

NAD+ is used to support energy, focus, and healthy aging. Here's how patients most commonly describe what they're looking for from an NAD+ protocol:

Cellular Energy

Supports cellular energy and metabolism by powering mitochondrial energy production at the cellular level.

Cognitive Clarity & Focus

Promotes cognitive clarity and focus, supporting sharper mental performance day to day.

Recovery

Aids in recovery — helping your body bounce back as part of an overall wellness routine.

Healthy Aging

Supports DNA repair and healthy cellular aging, an area of growing interest in longevity medicine.

A note on expectations

NAD+ is a wellness support, not a cure. It's most effective as part of a broader routine that includes sleep, nutrition, and movement, and individual results vary. Many patients add NAD+ alongside a GLP-1 weight loss plan for additional energy and recovery support.

Who Is NAD+ For?

NAD+ is commonly considered by adults who are:

  • Experiencing low energy or fatigue not explained by another condition
  • Looking to support mental clarity and focus day to day
  • Recovering from intense training, travel, or a demanding schedule
  • Interested in supporting healthy cellular aging as part of a broader wellness routine

NAD+ is prescribed after a brief online health assessment, so your clinician can confirm it's an appropriate fit for you before you start.

How NAD+ Is Administered

1stRX offers NAD+ as a clinician-prescribed injectable, compounded at a licensed pharmacy and shipped to your door.

Injectable

A high-dose injectable NAD+ option, self-administered subcutaneously, following your clinician's guidance.

NAD+ is prescribed after a quick online assessment, and your 1stRX clinician will guide you through dosing and administration.

NAD+ Injectable vs. IV Therapy

You may have seen NAD+ offered as an IV drip at wellness clinics. 1stRX offers NAD+ as a high-dose injectable instead — a small subcutaneous injection you administer yourself at home, rather than an infusion that requires an in-person clinic visit.

Which is right for you?

If you're looking for a clinician-prescribed option you can take on your own schedule without visiting an infusion clinic, injectable NAD+ is built for that. 1stRX does not currently offer IV infusion.

Safety Considerations

NAD+ is generally well-tolerated. The most commonly reported effects are mild and temporary — injection-site soreness, flushing or warmth, mild nausea, or a brief headache — and they're dose-dependent, which is why your clinician starts conservatively and adjusts based on how you respond.

NAD+ isn't appropriate for everyone. Always disclose your full medical history during your consultation so your clinician can confirm it's right for you.

Frequently Asked Questions

How is NAD+ administered?

1stRX offers NAD+ as a high-dose injectable, self-administered subcutaneously following your clinician's guidance. It's compounded at a licensed pharmacy and shipped to your door.

How long until I feel the effects?

Everyone responds differently, and individual results vary. NAD+ is used to support energy, focus, and healthy aging as part of an overall wellness routine rather than as a quick fix, so it works best with consistent use over time alongside good sleep, nutrition, and movement.

Is NAD+ safe?

NAD+ is prescribed by a licensed clinician after an online assessment and compounded at a licensed pharmacy. It is a compounded formulation and is not FDA-approved as a finished drug. As with any new therapy, always review your health history with your clinician before starting, and reach out to your care team with any questions or concerns.

What exactly is NAD+?

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme central to cellular energy production, DNA repair, and metabolic function. It powers mitochondrial energy production, and its levels decline with age — which is why some people choose to supplement it to support energy, focus, and healthy aging.

Do I need insurance or a prior prescription?

No insurance is required. Start with a quick online assessment; if NAD+ is appropriate for you, a licensed clinician will write the prescription and your medication is compounded and shipped to your door. Pricing is flat and transparent with no hidden fees.

How often will I take NAD+?

NAD+ injectable frequency is individualized. Most protocols involve injections a few times per week, especially early on, with your clinician adjusting your dose and schedule over time based on how you respond. There's no single fixed schedule — it's clinician-directed.

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* NAD+ is a compounded formulation prepared by a licensed compounding pharmacy. Compounded medications are not FDA-approved as finished drugs but are regulated under applicable pharmacy law. NAD+ is not a treatment or cure for any disease, and no statements on this page have been evaluated by the FDA. Individual results vary based on dosage, adherence, and other factors, and results are not guaranteed or typical. This page is for informational purposes only and does not constitute medical advice. Always consult with your clinician before starting any new medication.